ONO-0300302 |CAS:856689-51-5 Probechem Biochemicals

Chemical Structure : ONO-0300302

ONO-0300302 (ONO0300302;ONO 0300302)

Catalog No.: PC-60145Not For Human Use, Lab Use Only.

ONO-0300302 (ONO0300302) is a novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM.

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Biological Activity

ONO-0300302 (ONO0300302) is a novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM.
ONO-0300302 shows excellent in vivo efficacy, represents a best research tool available to LPA-related diseases.

Physicochemical Properties

M.Wt	477.601
Formula	C29H35NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(1-((2S,3S)-2-((2,3-dihydro-1H-inden-2-yl)methyl)-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl)-1H-pyrrol-3-yl)propanoic acid

References

1. Masahiko Terakado, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1281-1286.

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ONO-0300302 (ONO0300302;ONO 0300302)

Biological Activity

Physicochemical Properties

References

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