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OUL245

Chemical Structure : OUL245

CAS No.: 1023814-45-0

OUL245 (OUL-245)

Catalog No.: PC-25419Not For Human Use, Lab Use Only.

OUL245 is a potent, selective PARP2 inhibitor with IC50 of 44 nM, weakly inhibits multiple poly-ARTs at low μM concentration, does not inhibit mono-ARTs PARP7, PARP11, PARP12, PARP14, and PARP15.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

OUL245 is a potent, selective PARP2 inhibitor with IC50 of 44 nM, weakly inhibits multiple poly-ARTs at low μM concentration, does not inhibit mono-ARTs PARP7, PARP11, PARP12, PARP14, and PARP15.

Physicochemical Properties

M.Wt 191.21
Formula C8H5N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-7-ol

References

1. Murthy S, et al. J Med Chem. 2023 Jan 26;66(2):1301-1320.

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