Catalog No.: PC-35378Not For Human Use, Lab Use Only.
OUL35 (NSC39047) is a potent and selective inhibitor of mono-ADP-ribosyltransferase PARP10/ARTD10 with IC50 of 330 nM, displays remarkable selectivity towards ARTD10 over other enzymes in the human protein family.
OUL35 (NSC39047) is a potent and selective inhibitor of mono-ADP-ribosyltransferase PARP10/ARTD10 with IC50 of 330 nM, displays remarkable selectivity towards ARTD10 over other enzymes in the human protein family.
OUL35 rescues cells from ARTD10 induced cell death, sensitizes cancer cells to the hydroxyurea-induced genotoxic stress.
OUL35 is a cell biology tool compound for selective inhibition of ARTD10-mediated MARylation and investigation of ARTD10 in DNA-damage repair.
Physicochemical Properties
M.Wt
256.261
Formula
C14H12N2O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-(4-Carbamoylphenoxy)benzamide
References
1. Venkannagari H, et al. Cell Chem Biol. 2016 Oct 20;23(10):1251-1260.
2. Murthy S, et al. Eur J Med Chem. 2018 Jun 20;156:93-102.
