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OUN11211

Chemical Structure : OUN11211

CAS No.: 724711-21-1

OUN11211 (OUN 11211)

Catalog No.: PC-38026Not For Human Use, Lab Use Only.

OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM.
OUN11211 demonstrates exceptional selectivity against CDK2, ERK2, JNK2, IKK2, as well as MNK1, MSK1, and MSK2 (IC50=3->100 uM).

Physicochemical Properties

M.Wt 340.39
Formula C21H16N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one

References

1. David R Anderson, et al. J Med Chem. 2007 May 31;50(11):2647-54.

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