OUN11211 | MK2 inhibitor | Probechem Biochemicals

Chemical Structure : OUN11211

CAS No.: 724711-21-1

OUN11211 (OUN 11211)

Catalog No.: PC-38026Not For Human Use, Lab Use Only.

OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM.

Packing	Price	Stock
5 mg	$138	In stock
10 mg	$218	In stock
25 mg	$358	In stock
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Biological Activity

OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM.
OUN11211 demonstrates exceptional selectivity against CDK2, ERK2, JNK2, IKK2, as well as MNK1, MSK1, and MSK2 (IC50=3->100 uM).

Physicochemical Properties

M.Wt	340.39
Formula	C21H16N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one

References

1. David R Anderson, et al. J Med Chem. 2007 May 31;50(11):2647-54.

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OUN11211 (OUN 11211)

Biological Activity

Physicochemical Properties

References

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