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OXF-077

Chemical Structure : OXF-077

CAS No.:

OXF-077 (OXF077)

Catalog No.: PC-22567Not For Human Use, Lab Use Only.

OXF-077 is a potent inhibitor of the mutagenic SOS response, suppresses the rate of ciprofloxacin resistance emergence in S. aureus, is a potentiator of DNA-damage in MRSA.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

OXF-077 is a potent inhibitor of the mutagenic SOS response, suppresses the rate of ciprofloxacin resistance emergence in S. aureus, is a potentiator of DNA-damage in MRSA.

Physicochemical Properties

M.Wt 536.55
Formula C25H24F4N4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-fluoro-1-isopropyl-4-oxo-7-(4-((4-(trifluoromethyl)phenyl)carbamothioyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

References

1. Bradbury JD, et al. Chem Sci. 2024 May 16;15(25):9620-9629.

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