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Octreotide

Chemical Structure : Octreotide

CAS No.: 83150-76-9

Octreotide (SMS 201-995, SMS201-995)

Catalog No.: PC-22364Not For Human Use, Lab Use Only.

Octreotide (SMS 201-995) is an octapeptide that mimics natural somatostatin pharmacologically, that is 200 times more potent than somatostatin.

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Biological Activity

Octreotide (SMS 201-995) is an octapeptide that mimics natural somatostatin pharmacologically, that is 200 times more potent than somatostatin.
Octreotide (SMS 201-995) has also been shown to produce analgesic effects, most probably acting as a partial agonist at the mu opioid receptor.

Physicochemical Properties

M.Wt 1019.25
Formula C49H66N10O10S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

References

1. Maurer R, et al. Proc Natl Acad Sci U S A. 1982 Aug;79(15):4815-7.

2. Allen MP, et al. Bioorg Med Chem Lett. 2000 Mar 20;10(6):523-6.

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