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Chemical Structure : Odanacatib
CAS No.: 603139-19-1
Catalog No.: PC-42147Not For Human Use, Lab Use Only.
Odanacatib (MK-0822) is a potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 0.2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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Odanacatib (MK-0822) is a potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 0.2 nM.
Odanacatib (MK-0822) displays >300-fold selectivity over cathepsin B, L, S, F, and V.
Odanacatib (MK-0822) demonstrates the potentiation for the treatment of osteoporosis and other skeletal disorders associated with excessive bone remodeling.
| M.Wt | 525.5588 | |
| Formula | C25H27F4N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥25 mg/mL |
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| Chemical Name/SMILES |
Pentanamide, N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]-, (2S)- |
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1. Gauthier JY, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):923-8.
2. Kumar V, et al. Mol Pharm. 2009 Jul-Aug;6(4):1118-24.
3. Eisman JA, et al. J Bone Miner Res. 2011 Feb;26(2):242-51.
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