Chemical Structure : Odanacatib
CAS No.:
603139-19-1
Odanacatib
(MK-0822, MK0822)
Catalog No. : PC-42147Not For Human Use, Lab Use Only.
Odanacatib (MK-0822) is a potent, selective, reversible and orally active cathepsin K (CTSK) inhibitor with IC50 of 0.2 nM.
Packing Price Stock Quantity 2 mg $58 In stock 0 1 2 3 4 5 5 mg $98 In stock 0 1 2 3 4 5 10 mg $148 In stock 0 1 2 3 4 5 25 mg $268 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4214701
Biological Activity
Odanacatib (MK-0822) is a potent, selective, reversible and orally active cathepsin K (CTSK) inhibitor with IC50 of 0.2 nM.
Physicochemical Properties
M.Wt
525.5588
Formula
C25H27F4N3O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥25 mg/mL
Chemical Name/SMILES
Pentanamide, N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]-, (2S)-
References
1. Gauthier JY, et al. Bioorg Med Chem Lett.
2. Kumar V, et al. Mol Pharm.
3. Eisman JA, et al. J Bone Miner Res.
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