Oditrasertib (DNL788, SAR443820)

Chemical Structure : Oditrasertib

CAS No.: 2252271-93-3

Catalog No.: PC-20063Not For Human Use, Lab Use Only.

Oditrasertib (DNL788, SAR443820) is a potent, selective, orally bioavailable, brain penetrant inhibitor RIPK1 inhibitor with IC50 of 3.16 nM in human PBMCs and 1.6 nM in induced pluripotent stem cell (iPSC)‐derived microglia.

Packing	Price	Stock
5 mg	$358	In stock
10 mg	$528	In stock
25 mg	$898	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Oditrasertib (DNL788, SAR443820) is a potent, selective, orally bioavailable, brain penetrant inhibitor RIPK1 inhibitor with IC50 of 3.16 nM in human PBMCs and 1.6 nM in induced pluripotent stem cell (iPSC)‐derived microglia.

Physicochemical Properties

M.Wt	295.29
Formula	C14H15F2N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3,3-difluoro-2,2-dimethylpropanoyl)-2,3,4,5- tetrahydropyrido[3,4-f][1,4]oxazepine-9-carbonitrile

References

1. Patent WO2018213632 A1.
2. Hincelin-Mery A, et al. Clin Transl Sci. 2024 Jan;17(1):e13690.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com