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Chemical Structure : Oditrasertib
CAS No.: 2252271-93-3
Catalog No.: PC-20063Not For Human Use, Lab Use Only.
Oditrasertib (DNL788, SAR443820) is a potent, selective, orally bioavailable, brain penetrant inhibitor RIPK1 inhibitor with IC50 of 3.16 nM in human PBMCs and 1.6 nM in induced pluripotent stem cell (iPSC)‐derived microglia.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $358 | In stock | |
| 10 mg | $528 | In stock | |
| 25 mg | $898 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Oditrasertib (DNL788, SAR443820) is a potent, selective, orally bioavailable, brain penetrant inhibitor RIPK1 inhibitor with IC50 of 3.16 nM in human PBMCs and 1.6 nM in induced pluripotent stem cell (iPSC)‐derived microglia.
| M.Wt | 295.29 | |
| Formula | C14H15F2N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(3,3-difluoro-2,2-dimethylpropanoyl)-2,3,4,5- tetrahydropyrido[3,4-f][1,4]oxazepine-9-carbonitrile |
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1. Patent WO2018213632 A1.
2. Hincelin-Mery A, et al. Clin Transl Sci. 2024 Jan;17(1):e13690.
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