Ofatumumab
(Anti-human CD20 mAb, human IgG1-Kappa; GSK-1841157; HuMax CD20)
Catalog No.: PC-Ab1110Not For Human Use, Lab Use Only.
Ofatumumab (GSK-1841157, OMB157) is a fully humanized, high-affinity monoclonal antibody whose epitope on CD20 is distinct from rituximab’s target. Ofatumumab induces efficient complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity, even when CD20 expression is low. Ofatumumab inhibits early-stage B lymphocyte activation..
Ofatumumab (GSK-1841157, OMB157) is a fully humanized, high-affinity monoclonal antibody whose epitope on CD20 is distinct from rituximab’s target. Ofatumumab induces efficient complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity, even when CD20 expression is low. Ofatumumab inhibits early-stage B lymphocyte activation.
Physicochemical Properties
M.Wt
Formula
Human IgG1-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
