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Chemical Structure : Ogerin
CAS No.: 1309198-71-7
Catalog No.: PC-61084Not For Human Use, Lab Use Only.
Ogerin (ZINC 67740571) is a selective GPR68 positive allosteric modulator (pEC50=6.83) with minimal PAM activity at the related proton-sensing GPCRs GPR4 and GPR65.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $138 | In stock | |
| 25 mg | $248 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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Ogerin (ZINC 67740571) is a selective GPR68 positive allosteric modulator (pEC50=6.83) with minimal PAM activity at the related proton-sensing GPCRs GPR4 and GPR65.
Ogerin only shows moderate affinity at 5-HT2B and the A2A receptor in a panel of 58 GPCRs.
Ogerin attenuates contextual-based fear memory without effects on cue-based memory in mice.
| M.Wt | 307.35 | |
| Formula | C17H17N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol |
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1. Huang XP, et al. Nature. 2015 Nov 26;527(7579):477-83.
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