Chemical Structure : Ogremorphin-1
CAS No.: 352563-21-4
Catalog No.: PC-49418Not For Human Use, Lab Use Only.
Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM.
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Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM.
Ogremorphin-1 (OGM1) displays high selectivity against 158 GPCRs in a single point assay using Chem-1 cells.
Ogremorphin-1 (OGM1) could induce abnormal pigmentation during embryonic development, reproducibly induced ventral curvature, wavy notochord, shortened body axis, craniofacial defects, and loss of retinal iridophores.
Ogremorphin-1 (OGM1) disrupts development of neural crest–derived tissues subsequent to the formation of neural crest progenitors, most likely during neural crest migration.
M.Wt | 359.447 | |
Formula | C21H17N3OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-ethyl-5'-naphthalen-1-ylspiro[1H-indole-3,2'- 3H-1,3,4-thiadiazole]-2-one |
1. Charles H Williams, et al. Exp Hematol Oncol. 2024 Jan 31;13(1):13.
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