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Chemical Structure : Ogremorphin
Catalog No.: PC-49417Not For Human Use, Lab Use Only.
Ogremorphin (OGM, OGM8345) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.71 uM.
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Ogremorphin (OGM, OGM8345) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.71 uM, also inhibits ADAMTS-5.
Ogremorphin (OGM1, OGM8345) was discovered in a chemical genetic zebrafish screen for its ability to perturb neural crest development, which shares basic cell behaviors of migration and invasion with cancer metastasis.
Ogremorphin also inhibited migration and invasive behavior of neural crest–derived human melanoma cells in vitro.
| M.Wt | 309.387 | |
| Formula | C17H15N3OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Charles H Williams, et al. Exp Hematol Oncol. 2024 Jan 31;13(1):13.
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