Okicenone |CAS:137018-54-3 Probechem Biochemicals

Chemical Structure : Okicenone

Okicenone

Catalog No.: PC-60909Not For Human Use, Lab Use Only.

Okicenone is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 90 nM.

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Biological Activity

Okicenone is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 90 nM.
Okicenone interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation.
Okicenone is a valuable tool for studying HuR function.

Physicochemical Properties

M.Wt	258.273
Formula	C15H14O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4,6,9-trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one

References

1. Meisner NC, et al. Nat Chem Biol. 2007 Aug;3(8):508-15.

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Okicenone

Biological Activity

Physicochemical Properties

References

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