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Okicenone

Chemical Structure : Okicenone

CAS No.: 137018-54-3

Okicenone

Catalog No.: PC-60909Not For Human Use, Lab Use Only.

A small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 90 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 90 nM; interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation, and is a valuable tool for studying HuR function;

Physicochemical Properties

M.Wt 258.273
Formula C15H14O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,6,9-trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one

References

1. Meisner NC, et al. Nat Chem Biol. 2007 Aug;3(8):508-15.

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