Chemical Structure : Olinciguat
CAS No.: 1628732-62-6
Catalog No.: PC-60523Not For Human Use, Lab Use Only.
Olinciguat (IW-1701, IW1701) is a novel potent, selective soluble guanylate cyclase (sGC) stimulator, enhances the synthesis of cGMP in response to NO binding.
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M.Wt | 509.4 | |
Formula | C21H16F5N7O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(2R)-3,3,3-trifluoro-2-{[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]- 5-(1,2-oxazol-3-yl)-1H-pyrazol- 3-yl}pyrimidin-4-yl)amino]methyl}-2-hydroxypropanamide |
1. Tchernychev B, et al. Br J Pharmacol. 2021 Sep;178(17):3463-3475.
2. Zimmer DP, et al. Front Pharmacol. 2020 Apr 8;11:419.
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