Olisutrigine bromide | Sodium channel blocker

Chemical Structure : Olisutrigine bromide

Olisutrigine bromide (EN3427)

Catalog No.: PC-24162Not For Human Use, Lab Use Only.

Olisutrigine bromide (EN3427) is a novel permanently charged cationic sodium channel blocker, produces effective and long-lasting analgesia in rodent pain models.

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Biological Activity

Olisutrigine bromide (EN3427) is a novel permanently charged cationic sodium channel blocker, produces effective and long-lasting analgesia in rodent pain models.

Physicochemical Properties

M.Wt	443.47
Formula	C25H35BrN2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(2-((2,3-dihydro-1H-inden-2-yl)(o-tolyl)amino)ethyl)-1,1-dimethylpiperidin-1-ium bromide

References

1. Manish Banerjee, et al. Anesth Analg. 2015 Apr;120(4):941-9.

2. Patent WO2020113050 A1.

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Olisutrigine bromide (EN3427)

Biological Activity

Physicochemical Properties

References

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