Chemical Structure : Olodaterol
CAS No.: 868049-49-4
Catalog No.: PC-43903Not For Human Use, Lab Use Only.
Olodaterol (BI 1744) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.
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Olodaterol (BI 1744) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.
Olodaterol shows >250 fold selectivity over hβ1.
Olodaterol exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.
| M.Wt | 386.4415 | |
| Formula | C21H26N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 6.2 mg/mL |
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| Chemical Name/SMILES |
2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]- |
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1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.

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