Chemical Structure : Olodaterol hydrochloride
CAS No.: 869477-96-3
Catalog No.: PC-36084Not For Human Use, Lab Use Only.
Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.
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Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.
COPD
Phase 3 Clinical
M.Wt | 413.895 | |
Formula | C21H17ClFN3OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine hydrochloride |
1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.
2. Bouyssou T, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):53-62.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
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