Chemical Structure : Olodaterol hydrochloride
CAS No.:
869477-96-3
Olodaterol hydrochloride
(BI1744 CL)
Catalog No. : PC-36084Not For Human Use, Lab Use Only.
Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3608401
Biological Activity
Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.
COPD
Phase 3 Clinical
Physicochemical Properties
M.Wt
413.895
Formula
C21H17ClFN3OS
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine hydrochloride
References
1. Bouyssou T, et al. Bioorg Med Chem Lett.
2. Bouyssou T, et al. J Pharmacol Exp Ther.
3. Wex E, et al. Br J Pharmacol.
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