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Chemical Structure : Olumacostat glasaretil
CAS No.: 1261491-89-7
Catalog No.: PC-45395Not For Human Use, Lab Use Only.
Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC).
Olumacostat glasaretil (DRM01) inhibits de novo lipid synthesis in primary and transformed human sebocytes; reduces saturated and monounsaturated fatty acyl chains across lipid species, including di- and triacylglycerols, phospholipids, cholesteryl esters, and wax esters.
Olumacostat glasaretil (DRM01) significantly reduces hamster ear sebaceous gland size.
Olumacostat glasaretil (DRM01) a pro-drug of TOFA with enhance delivery in vivo.
| M.Wt | 481.6221 | |
| Formula | C26H43NO7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Furancarboxylic acid, 5-(tetradecyloxy)-, 2-[(2-ethoxy-2-oxoethyl)methylamino]-2-oxoethyl ester |
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1. Bissonnette R, et al. J Am Acad Dermatol. 2017 Jan;76(1):33-39.
2. Hunt DW, et al. J Invest Dermatol. 2017 Jul;137(7):1415-1423.
3. Melnik BC. J Invest Dermatol. 2017 Jul;137(7):1405-1408.
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