Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Ombrabulin
CAS No.: 181816-48-8
Catalog No.: PC-70178Not For Human Use, Lab Use Only.
Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ.
Ombrabulin is a vascular-disrupting agent under clinical investigation combined with cisplatin/docetaxel or carboplatin/paclitaxel in patients with advanced solid tumors.
| M.Wt | 402.45 | |
| Formula | C21H26N2O6 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(2S)-2-Amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide |
|
1. Kim TJ, et al. Cancer Res. 2007 Oct 1;67(19):9337-45.
2. Hori K, et al. Cancer Sci. 2008 Jul;99(7):1485-91.
3. Hori K, et al. Br J Cancer. 2002 May 20;86(10):1604-14.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
