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Omidenepag

Chemical Structure : Omidenepag

CAS No.: 1187451-41-7

Omidenepag (UR-7276, UR7276)

Catalog No.: PC-35402Not For Human Use, Lab Use Only.

Omidenepag (UR-7276) is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Omidenepag (UR-7276) is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors.
Omidenepag is the active form of Omidenepag Isopropyl (OMDI).

Physicochemical Properties

M.Wt 478.527
Formula C23H22N6O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(6-((4-(Pyrazol-1-yl)benzyl)(pyridin-3-ylsulfonyl)aminomethyl)pyridin-2-ylamino)acetic acid

References

1. Kirihara T, et al. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):145-153.

2. Impagnatiello F, et al. Br J Pharmacol. 2018 Apr 18. doi: 10.1111/bph.14328.

3. Fuwa M, et al. J Ocul Pharmacol Ther. 2018 Jul 10. doi: 10.1089/jop.2017.0146.

4. Iwamura R, et al. J Med Chem. 2018 Jul 11. doi: 10.1021/acs.jmedchem.8b00808.

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