Chemical Structure : Omidenepag
CAS No.: 1187451-41-7
Catalog No.: PC-35402Not For Human Use, Lab Use Only.
Omidenepag (UR-7276) is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors.
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Omidenepag (UR-7276) is a potent, selective agonist human EP2 receptor with binding IC50/EC50 of 10/1.7 nM, >500-fold selectivity over EP1, EP3 and EP4 receptors.
Omidenepag is the active form of Omidenepag Isopropyl (OMDI).
| M.Wt | 478.527 | |
| Formula | C23H22N6O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(6-((4-(Pyrazol-1-yl)benzyl)(pyridin-3-ylsulfonyl)aminomethyl)pyridin-2-ylamino)acetic acid |
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1. Kirihara T, et al. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):145-153.
2. Impagnatiello F, et al. Br J Pharmacol. 2018 Apr 18. doi: 10.1111/bph.14328.
3. Fuwa M, et al. J Ocul Pharmacol Ther. 2018 Jul 10. doi: 10.1089/jop.2017.0146.
4. Iwamura R, et al. J Med Chem. 2018 Jul 11. doi: 10.1021/acs.jmedchem.8b00808.

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