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Onapristone

Chemical Structure : Onapristone

CAS No.: 96346-61-1

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Onapristone (ZK-89299, ZK-299, AR-18, IVV-1001)

Catalog No.: PC-60075Not For Human Use, Lab Use Only.

Onapristone (ZK-89299, ZK-299) is a synthetic, steroidal progesterone receptor (PR) antagonist with reduced antiglucocorticoid activity compared to mifepristone.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Onapristone (ZK-89299, ZK-299) is a synthetic, steroidal progesterone receptor (PR) antagonist with reduced antiglucocorticoid activity compared to mifepristone.

    Physicochemical Properties

    M.Wt 449.635
    Formula C29H39NO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    11β-(4-(Dimethylamino)phenyl)-17α-hydroxy-17β-(3-hydroxypropyl)-13α-estra-4,9-dien-3-one

    References

    1. Michna H, et al. Breast Cancer Res Treat. 1989 Dec;14(3):275-88.

    2. Schneider MR, et al. J Cancer Res Clin Oncol. 1992;118(3):187-9.

    3. Mann GE, et al. Mol Cell Endocrinol. 2013 Aug 25;376(1-2):1-11.

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