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Ondansetron

Chemical Structure : Ondansetron

CAS No.: 99614-02-5

Ondansetron (GR 38032, SN 307)

Catalog No.: PC-23333Not For Human Use, Lab Use Only.

Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.
Ondansetron shows negligible agonist or antagonist activity on other 5-HT or non-5-HT receptor-containing tissues.
Ondansetron antagonizes the bradycardic response to 5-HT or 2-methyl-5-HT administered intravenously (i.v.) to anaesthetized animals.

Physicochemical Properties

M.Wt 293.37
Formula C18H19N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one

References

1. Butler A, et al. Br J Pharmacol. 1988 Jun;94(2):397-412.

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