Ondansetron hydrochloride | 5-HT3 antagonist

Chemical Structure : Ondansetron hydrochloride

CAS No.: 99614-01-4

Ondansetron hydrochloride (GR 38032, SN 307)

Catalog No.: PC-23334Not For Human Use, Lab Use Only.

Ondansetron hydrochloride (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.

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500 mg	$158	In stock
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Biological Activity

Ondansetron hydrochloride (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.
Ondansetron shows negligible agonist or antagonist activity on other 5-HT or non-5-HT receptor-containing tissues.
Ondansetron antagonizes the bradycardic response to 5-HT or 2-methyl-5-HT administered intravenously (i.v.) to anaesthetized animals.

Physicochemical Properties

M.Wt	329.83
Formula	C18H20ClN3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride

References

1. Butler A, et al. Br J Pharmacol. 1988 Jun;94(2):397-412.

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Ondansetron hydrochloride (GR 38032, SN 307)

Biological Activity

Physicochemical Properties

References

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