Chemical Structure : Ondansetron hydrochloride dihydrate
CAS No.: 103639-04-9
Catalog No.: PC-23335Not For Human Use, Lab Use Only.
Ondansetron hydrochloride dihydrate (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.
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Ondansetron hydrochloride dihydrate (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.
Ondansetron shows negligible agonist or antagonist activity on other 5-HT or non-5-HT receptor-containing tissues.
Ondansetron antagonizes the bradycardic response to 5-HT or 2-methyl-5-HT administered intravenously (i.v.) to anaesthetized animals.
M.Wt | 365.86 | |
Formula | C18H24ClN3O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride dihydrate |
1. Butler A, et al. Br J Pharmacol. 1988 Jun;94(2):397-412.
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