Onzotrigine | Nav1.8 inhibitor | Probechem Biochemicals

Chemical Structure : Onzotrigine

Catalog No.: PC-27490Not For Human Use, Lab Use Only.

Onzotrigine (LTG-001) is a potent, selective voltage-gated sodium channel Nav1.8 inhibitor.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Onzotrigine (LTG-001) is a potent, selective voltage-gated sodium channel Nav1.8 inhibitor.

M.Wt	484.47
Formula	C21H20F4N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((6-fluoro-2-methylpyridin-3-yl)oxy)-4-methyl-1-(3-(S-methylsulfonimidoyl)phenyl)-5-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide

1. Patent WO2022192487 A2 2022-09-15.

2. Neil Singla, et al. N Engl J Med. 2026 Jul 30;395(5):454-464.