Org24598 | GlyT1 inhibitor | Probechem Biochemicals

Chemical Structure : Org24598

Org24598 (Org 24598)

Catalog No.: PC-23734Not For Human Use, Lab Use Only.

Org24598 is a potent, selective glycine transporter 1 (GlyT1) inhibitor with pIC50 of 6.9 (GlyT-1b), shows negligible activity at hGlyT-2 (pIC50 <4.0).

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Org24598 is a potent, selective glycine transporter 1 (GlyT1) inhibitor with pIC50 of 6.9 (GlyT-1b), shows negligible activity at hGlyT-2 (pIC50 <4.0).
Org24598 is approximately 600× more potent than sarcosine.
Org24598 exhibits glycine uptake inhibition (GUI) activity in vivo.

Physicochemical Properties

M.Wt	367.37
Formula	C19H20F3NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(Methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)amino)acetic acid

References

1. Brown A, et al. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2007-9.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

Org24598 (Org 24598)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.