Chemical Structure : Org 42599 free base
CAS No.: 501444-88-8
Catalog No.: PC-62756Not For Human Use, Lab Use Only.
Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).
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Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).
M.Wt | 514.663 | |
Formula | C24H30N6O3S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-amino-N-(tert-butyl)-2-(methylthio)-4-(3-(2-morpholinoacetamido)phenyl)thieno[2,3-d]pyrimidine-6-carboxamide |
1. Newton CL, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7172-6.
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