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Ouabain

Chemical Structure : Ouabain

CAS No.: 630-60-4

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Ouabain

Catalog No.: PC-26300Not For Human Use, Lab Use Only.

Ouabain is a cardiac glycoside possessing cytotoxicity and anti-apoptotic effects, is a specific pumping function inhibitor of Na+/K+-ATPase, induces apoptosis in Jurkat cells with IC50 of 26 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ouabain is a cardiac glycoside possessing cytotoxicity and anti-apoptotic effects, is a specific pumping function inhibitor of Na+/K+-ATPase, induces apoptosis in Jurkat cells with IC50 of 26 nM.

Physicochemical Properties

M.Wt 584.65
Formula C29H44O12
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one

References

1. Mayr C, et al. PLoS One. 2023 Jun 30;18(6):e0287769.

2. Ismaili D, et al. Br J Pharmacol. 2026 Feb 23. doi: 10.1111/bph.70380.

3. Ihenetu K, et al. Clin Chem. 2007 Jul;53(7):1315-22.

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