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Oxiconazole nitrate

Chemical Structure : Oxiconazole nitrate

CAS No.: 64211-46-7

Oxiconazole nitrate (Sgd 301-76)

Catalog No.: PC-27944Not For Human Use, Lab Use Only.

Oxiconazole nitrate (Sgd 301-76) is a broad spectrum antifungal agent, shows fungicidal activity of for Aspergillus fumigatus, Cryptococcus neoformans, Candida albicans and Trichophyton mentagrophytes, also is a highly efficacious activator of CYP3A4 transactivation, exhibits certain anti-tumor effect against CRC via PRDX2-mediated autophagy arrest.

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Biological Activity

Oxiconazole nitrate (Sgd 301-76) is a broad spectrum antifungal agent, shows fungicidal activity of for Aspergillus fumigatus, Cryptococcus neoformans, Candida albicans and Trichophyton mentagrophytes, also is a highly efficacious activator of CYP3A4 transactivation, exhibits certain anti-tumor effect against CRC via PRDX2-mediated autophagy arrest.

Physicochemical Properties

M.Wt 492.13
Formula C18H14Cl4N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanone O-(2,4-dichlorobenzyl) oxime nitrate

References

1. Polak A. Arzneimittelforschung. 1982;32(1):17-24.

2. Svecova L, et al. Drug Metab Dispos. 2008 Feb;36(2):339-48.

3. Shi J, et al. Int J Biol Sci. 2022 May 21;18(9):3747-3761.

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