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Ozenoxacin

Chemical Structure : Ozenoxacin

CAS No.: 245765-41-7

Ozenoxacin (T-3912, T3912)

Catalog No.: PC-28150Not For Human Use, Lab Use Only.

Ozenoxacin (T-3912) is a quinolone-class antibiotic inhibiting DNA gyrase and topoisomerase IV, shows potent antibacterial activity against anaerobic and aerobic, gram-positive and -negative bacteria, has demonstrates excellent in vitro activity against MRSA and methicillin-resistant Staphylococcus epidermidis (MRSE), including quinolone-resistant strains.

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Biological Activity

Ozenoxacin (T-3912) is a quinolone-class antibiotic inhibiting DNA gyrase and topoisomerase IV, shows potent antibacterial activity against anaerobic and aerobic, gram-positive and -negative bacteria, has demonstrates excellent in vitro activity against MRSA and methicillin-resistant Staphylococcus epidermidis (MRSE), including quinolone-resistant strains.

Physicochemical Properties

M.Wt 363.42
Formula C21H21N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Cyclopropyl-8-methyl-7-(5-methyl-6-(methylamino)pyridin-3-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

References

1. Nakajima A, et al. J Med Microbiol. 2016 Aug;65(8):745-750.

2. López Y, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6389-92.

3. Tato M, et al. Diagn Microbiol Infect Dis. 2014 Mar;78(3):263-7.

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