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PAβN dihydrochloride

Chemical Structure : PAβN dihydrochloride

CAS No.: 100929-99-5

PAβN dihydrochloride (MC-207,110, Phe-Arg-β-naphthylamide dihydrochloride )

Catalog No.: PC-26647Not For Human Use, Lab Use Only.

PAβN dihydrochloride (MC-207,110) is a potent efflux pump inhibitor that potentiates effect of the activity of levofloxacin against both laboratory strains with multiple target mutations and recent clinical isolates of P. aeruginosa.

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Biological Activity

PAβN dihydrochloride (MC-207,110) is a potent efflux pump inhibitor that potentiates effect of the activity of levofloxacin against both laboratory strains with multiple target mutations and recent clinical isolates of P. aeruginosa.

Physicochemical Properties

M.Wt 519.47
Formula C25H32Cl2N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-((S)-2-Amino-3-phenylpropanamido)-5-guanidino-N-(naphthalen-2-yl)pentanamide dihydrochloride

References

1. Lomovskaya O, et al. Antimicrob Agents Chemother. 2001 Jan;45(1):105-16.

2. Lamers RP, et al. PLoS One. 2013;8(3):e60666.

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