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PAC1

Chemical Structure : PAC1

CAS No.: 2158322-33-7

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PAC1 (Compound PAC1)

Catalog No.: PC-35040Not For Human Use, Lab Use Only.

PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation.

    Physicochemical Properties

    M.Wt 1674.93
    Formula C94H107N13O16
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-((2S,3S)-8-Cyano-5-((2-methoxynaphthalen-1-yl)methyl)-2-methyl-3-((S)-2-(methylamino)propanamido)-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-1-carbonyl)-N-(2-(2-(2-((2-(4-((Z)-1-(4-((4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexan

    References

    1. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.

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