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PAD-PF1

Chemical Structure : PAD-PF1

CAS No.:

PAD-PF1

Catalog No.: PC-25182Not For Human Use, Lab Use Only.

PAD-PF1 is a small molecule potein arginine deiminase (PAD) inhibitor with binding KD of 2.82 uM and IC50 of 15.9 uM (PAD4).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PAD-PF1 is a small molecule potein arginine deiminase (PAD) inhibitor with binding KD of 2.82 uM and IC50 of 15.9 uM (PAD4).
PAD-PF1 binds to an allosteric site distinct from substrate and GSK147.

Physicochemical Properties

M.Wt 511.47
Formula C25H31BrN6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-amino-2-(1-(1-(5-bromopyridin-2-yl)-2,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-4-yl)piperidin-4-yl)-1-(pyrrolidin-1-yl)ethan-1-one

References

1. Dakin LA, et al. Nat Commun. 2025 May 16;16(1):4579.

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