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Chemical Structure : PAD2 inhibitor 32a
Catalog No.: PC-20326Not For Human Use, Lab Use Only.
PAD2 inhibitor 32a (AFM32a) is a potent, selective protein arginine deiminase 2 (PAD2) inhibitor with IC50 of EC50 of 8.3 uM in target engagement assays in HEK293/PAD2 cells.
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PAD2 inhibitor 32a (AFM32a) is a potent, selective protein arginine deiminase 2 (PAD2) inhibitor with IC50 of EC50 of 8.3 uM in target engagement assays in HEK293/PAD2 cells.
PAD2 inhibitor 32a exhibits 95-fold selectivity for PAD2 over PAD4 and 79-fold selectivity for PAD2 over PAD3, based on kinact/KI values.
| M.Wt | 480.54 | |
| Formula | C25H29FN6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Muth A, et al. Development of a Selective Inhibitor of Protein Arginine Deiminase 2. J Med Chem. 2017.
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