PAD3 inhibitor 14b | PAD3 inhibitor | Probechem Biochemicals

Chemical Structure : PAD3 inhibitor 14b

PAD3 inhibitor 14b (CAY10727)

Catalog No.: PC-25181Not For Human Use, Lab Use Only.

PAD3 inhibitor 14b is a potent and selective inhibitor of protein arginine deiminase PAD3 with kinact/KI value of 15600, ≥10-fold selectivity for PAD3 over PADs 1, 2, and 4.

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Biological Activity

PAD3 inhibitor 14b is a potent and selective inhibitor of protein arginine deiminase PAD3 with kinact/KI value of 15600, ≥10-fold selectivity for PAD3 over PADs 1, 2, and 4.

Physicochemical Properties

M.Wt	433.33
Formula	C21H22Cl2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-chloro-N-(3-(1-((2'-chloro-[1,1'-biphenyl]-3-yl)methyl)-2,5-dioxoimidazolidin-4-yl)propyl)acetimidamide

References

1. Jamali H, et al. J Am Chem Soc. 2015 Mar 18;137(10):3616-21.

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PAD3 inhibitor 14b (CAY10727)

Biological Activity

Physicochemical Properties

References

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