PARP10-15 inhibitor 8l | PARP10 inhibitor

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Chemical Structure : PARP10-15 inhibitor 8l

PARP10-15 inhibitor 8l (PARP10/15-IN-1)

Catalog No.: PC-25417Not For Human Use, Lab Use Only.

PARP10-15 inhibitor 8l (PARP10/15-IN-1) is a potent, dual inhibitor of mono-ADP-ribosyltransferases PARP10 and PARP15 with IC50 of 160 nM and 370 nM respectively, inactive against the other mono-ARTs, PARP12 and PARP16.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	274.29
Formula	C13H10N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,3-Dihydro-6-(3-thienylmethoxy)-1,4-phthalazinedione

References

1. Nizi MG, et al. Eur J Med Chem. 2022 Jul 5;237:114362.

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PARP10-15 inhibitor 8l (PARP10/15-IN-1)

Biological Activity

Physicochemical Properties

References

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