PARP10 inhibitor 22 |CAS 2286261-72-9 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-PARP-PARP10 inhibitor 22

Chemical Structure : PARP10 inhibitor 22

PARP10 inhibitor 22

Catalog No.: PC-36012Not For Human Use, Lab Use Only.

PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members.

Packing	Price	Stock	Quantity
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members.
PARP10 inhibitor 22 inhibits PARP10-dependent MARylation in cells.
PARP10 inhibitor 22 is a useful probe to study PARP10 biology when combined with other PARP10-selective probes with different selectivity profiles.

Physicochemical Properties

M.Wt	306.288
Formula	C16H13F3N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-methyl-6-(2-(trifluoromethyl)pyridin-4-yl)-3,4-dihydroisoquinolin-1(2H)-one

References

1. Morgan RK, et al. ACS Med Chem Lett. 2018 Nov 29;10(1):74-79.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com