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Chemical Structure : PARP10 inhibitor 22
Catalog No.: PC-36012Not For Human Use, Lab Use Only.
PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members.
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PARP10 inhibitor 22 is a selective, cell-active inhibitor of PARP10 with IC50 of 1.8 uM, exhibits >10-fold selectivity over a large subset of other PARP family members.
PARP10 inhibitor 22 inhibits PARP10-dependent MARylation in cells.
PARP10 inhibitor 22 is a useful probe to study PARP10 biology when combined with other PARP10-selective probes with different selectivity profiles.
| M.Wt | 306.288 | |
| Formula | C16H13F3N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Morgan RK, et al. ACS Med Chem Lett. 2018 Nov 29;10(1):74-79.
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