Chemical Structure : PB28 dihydrochloride
CAS No.:
172907-03-8
PB28 dihydrochloride
(PB 28 dihydrochloride)
Catalog No. : PC-60346Not For Human Use, Lab Use Only.
PB28 dihydrochloride is a potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6034601
Biological Activity
PB28 dihydrochloride is a potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively.
Physicochemical Properties
M.Wt
443.5
Formula
C24H40Cl2N2O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine dihydrochloride
References
1. Azzariti A, et al. Mol Cancer Ther. 2006 Jul;5(7):1807-16.
2. Cassano G, et al. Cell Calcium. 2006 Jul;40(1):23-8.
3. Berardi F, et al. J Med Chem. 1996 Jan 5;39(1):176-82.
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