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Chemical Structure : PBOX-15
Catalog No.: PC-60561Not For Human Use, Lab Use Only.
PBOX-15 is a microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells.
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PBOX-15 is a microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells.
PBOX-15 radiosensitizes cancer cells in vitro, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours.
| M.Wt | 417.464 | |
| Formula | C28H19NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mulligan JM, et al. Mol Pharmacol. 2006 Jul;70(1):60-70.
2. Verma NK, et al. J Mol Med (Berl). 2008 Apr;86(4):457-69.
3. McElligott AM, et al. Cancer Res. 2009 Nov 1;69(21):8366-75.
4. Maginn EN, et al. Br J Cancer. 2011 Jan 18;104(2):281-9.
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