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PBZ1587

Chemical Structure : PBZ1587

CAS No.: 2247719-94-2

PBZ1587 (PBZ 1587)

Catalog No.: PC-22849Not For Human Use, Lab Use Only.

PBZ1587 is a small-molecule inhibitor of the GroES/GroEL chaperone system with IC50 of 0.44 uM in MDH refolding assay, binds at the GroEL ring–ring interface (RRI).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PBZ1587 is a small-molecule inhibitor of the GroES/GroEL chaperone system with IC50 of 0.44 uM in MDH refolding assay, binds at the GroEL ring–ring interface (RRI).

Physicochemical Properties

M.Wt 575.07
Formula C24H19ClN4O5S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(4-((4-(aminomethyl)phenyl)sulfonamido)phenyl)benzo[d]oxazol-5-yl)-5-chlorothiophene-2-sulfonamide

References

1. Jack Godek, et al. J Am Chem Soc. 2024 Jul 31;146(30):20845-20856.

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