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PCI-32765 racemate

Chemical Structure : PCI-32765 racemate

CAS No.: 936563-87-0

PCI-32765 racemate (Ibrutinib racemate, PCI 32765 racemate)

Catalog No.: PC-42773Not For Human Use, Lab Use Only.

Ibrutinib racemate (PCI-32765 racemate) is the racemate form of Ibrutinib, which is a potent, highly selective and covament Btk inhibitor with IC50 of 0.5 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ibrutinib racemate (PCI-32765 racemate) is the racemate form of Ibrutinib, which is a potent, highly selective and covament Btk inhibitor with IC50 of 0.5 nM.

Physicochemical Properties

M.Wt 440.4971
Formula C25H24N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Propen-1-one, 1-[3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-

References

1. Honigberg LA, et al. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

2. Herman SE, et al. Blood. 2014 May 22;123(21):3286-95.

3. Kohrt HE, et al. Blood. 2014 Mar 20;123(12):1957-60.

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