Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Others-PCSK9-PCSK9 inhibitor 9
PCSK9 inhibitor 9

Chemical Structure : PCSK9 inhibitor 9

CAS No.: 2215931-60-3

PCSK9 inhibitor 9

Catalog No.: PC-38279Not For Human Use, Lab Use Only.

PCSK9 inhibitor 9 is a small-molecule ligand with high affinity for a novel allosteric binding site on PCSK9.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PCSK9 inhibitor 9 is a small-molecule ligand with high affinity for a novel allosteric binding site on PCSK9.
    PCSK9 inhibitor 9 showed good target engagement with PCSK9 in Huh7 cell lysate.

    Physicochemical Properties

    M.Wt 631.719
    Formula C34H34FN3O6S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2'-fluoro-4'-(((1R)-1-methyl-1-(2-oxo-2-(thiazol-2-ylamino)ethyl)-6-((tetrahydro-2H-pyran-2-yl)methoxy)-1,2,3,4-tetrahydroisoquinolin-7-yl)oxy)-[1,1'-biphenyl]-4-carboxylic acid

    References

    1. Whitney L Petrilli, et al. Cell Chem Biol. 2020 Jan 16;27(1):32-40.e3.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: