You are here:Home-Chemical Inhibitors & Agonists-Tyrosine Kinase-FLT3-PCW-A1001
PCW-A1001

Chemical Structure : PCW-A1001

CAS No.: 3038800-54-0

PCW-A1001 (FLT3 D835Y mutant inhibitor)

Catalog No.: PC-20211Not For Human Use, Lab Use Only.

PCW-A1001 is a potent, selective inhibitor of FLT-3 (D835Y) mutant with IC50 of 764 nM, weakly inhibits WT FLT-3 with IC50 of 2.54 uM.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PCW-A1001 is a potent, selective inhibitor of FLT-3 (D835Y) mutant with IC50 of 764 nM, weakly inhibits WT FLT-3 with IC50 of 2.54 uM.
    PCW-A1001 inhibited the proliferation of MV4-11 cells with IC50 of 1.98 uM.

    Physicochemical Properties

    M.Wt 394.52
    Formula C23H30N4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(tert-butyl)-N-(4-carbamoyl-3-(piperidin-3-ylamino)phenyl)benzamide

    References

    1. Seong Hun Jang, et al. Front Mol Biosci. 2022 Nov 25;9:1072028.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: