PD-156707 | ETA receptor antagonist | Probechem Biochemicals

Chemical Structure : PD-156707

PD-156707 (PD 156707, PD156707)

Catalog No.: PC-26608Not For Human Use, Lab Use Only.

PD-156707 is a potent, selective and orally active non-peptide endothelin-A (ETA) receptor antagonist with Ki of 0.17 nM, >500-fold selective over ET-B receptor.

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Biological Activity

PD-156707 is a potent, selective and orally active non-peptide endothelin-A (ETA) receptor antagonist with Ki of 0.17 nM, >500-fold selective over ET-B receptor.

Physicochemical Properties

M.Wt	528.49
Formula	C28H25NaO9
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium (Z)-2-(benzo[d][1,3]dioxol-5-yl)-4-(4-methoxyphenyl)-4-oxo-3-(3,4,5-trimethoxybenzyl)but-2-enoate

References

1. Reynolds EE, et al. J Pharmacol Exp Ther. 1995 Jun;273(3):1410-7.

2. Doherty AM, et al. J Med Chem. 1995 Apr 14;38(8):1259-63.

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PD-156707 (PD 156707, PD156707)

Biological Activity

Physicochemical Properties

References

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