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Chemical Structure : PD151746
CAS No.: 181765-30-0
Catalog No.: PC-45704Not For Human Use, Lab Use Only.
PD151746 (PD 151746) is a potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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PD151746 (PD 151746) is a potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain.
PD151746 displays 20-fold selectivity over m-calpain; attenuates the SLLVY-AMC hydrolysis induced by maitotoxin in SY5Y cells.
PD151746 decreases cytotoxicity induced by oxidized low-density lipoprotein (oxLDL) in HMEC-1 cells.
| M.Wt | 237.2501 | |
| Formula | C11H8FNO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 37 mg/mL |
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| Chemical Name/SMILES |
(Z)-3-(5-fluoro-1H-indol-3-yl)-2-mercaptoacrylic acid |
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1. Wang KK, et al. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
2. Porn-Ares MI, et al. Biochem J. 2003 Sep 1;374(Pt 2):403-11.
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