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Chemical Structure : PD 169316
CAS No.: 152121-53-4
Catalog No.: PC-42662Not For Human Use, Lab Use Only.
PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM.
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|---|---|---|---|
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| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
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PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM.
PD 169316 displays >100-fold selectivity over ERK, PKA, PKCα.
PD 169316 prevent p38 phosphorylation while promotes the phosphorylation of the pro-survival SAPK/JNK and ERK;
| M.Wt | 360.3412 | |
| Formula | C20H13FN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Pyridine, 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]- |
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1. Gallagher TF, et al. Bioorg Med Chem. 1997 Jan;5(1):49-64.
2. Krishnamoorthy M, et al. J Biochem. 2009 Feb;145(2):177-84.
3. Kozawa O, et al. Cell Signal. 2000 Jul;12(7):447-50.
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