Chemical Structure : PD173952
CAS No.: 305820-75-1
Catalog No.: PC-22637Not For Human Use, Lab Use Only.
PD173952 is a multi-kinases inhibitor with IC50 of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk kinase respectively, induces apoptosis of Bcr-Abl-dependent hematopoietic cells.
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PD173952 is a multi-kinases inhibitor with IC50 of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk kinase respectively, induces apoptosis of Bcr-Abl-dependent hematopoietic cells.
M.Wt | 482.37 | |
Formula | C24H21Cl2N5O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
6-(2,6-Dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one |
1. Dorsey JF, et al. Leukemia. 2002 Sep;16(9):1589-95.
2. Marshall SJ, et al. Blood. 2004 Apr 1;103(7):2601-9.
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