PDCD2 ligand 7e | PDCD2 modulator | Probechem Biochemicals

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Chemical Structure : PDCD2 ligand 7e

PDCD2 ligand 7e (PDCD2 modulator)

Catalog No.: PC-21117Not For Human Use, Lab Use Only.

PDCD2 ligand 7e is a small molecule that may directly bind to programmed cell death 2 (PDCD2), rescues PDCD2 degradation induced by PDCD2 degrader 10e.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PDCD2 ligand 7e is a small molecule that may directly bind to programmed cell death 2 (PDCD2), rescues PDCD2 degradation induced by PDCD2 degrader 10e.
Programmed cell death 2 (PDCD2) is a member of the B-cell lymphoma 2 (Bcl-2) family of proteins, which are critical regulators of apoptosis.

Physicochemical Properties

M.Wt	618.70
Formula	C35H37F3N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl (S)-4-((6-(1-(5-(4-(trifluoromethyl)phenyl)-2-naphthamido)ethyl)pyridin-2-yl)amino)piperidine-1-carboxylate

References

1. Wenzhi Ji, et al. Angew Chem Int Ed Engl. 2023 Sep 1;e202308292.

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