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PDCD2 ligand 7e

Chemical Structure : PDCD2 ligand 7e

CAS No.:

PDCD2 ligand 7e (PDCD2 modulator)

Catalog No.: PC-21117Not For Human Use, Lab Use Only.

PDCD2 ligand 7e is a small molecule that may directly bind to PDCD2, rescues PDCD2 degradation induced by PDCD2 degrader 10e.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDCD2 ligand 7e is a small molecule that may directly bind to PDCD2, rescues PDCD2 degradation induced by PDCD2 degrader 10e.
Programmed cell death 2 (PDCD2) is a member of the B-cell lymphoma 2 (Bcl-2) family of proteins, which are critical regulators of apoptosis.

Physicochemical Properties

M.Wt 618.70
Formula C35H37F3N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

tert-butyl (S)-4-((6-(1-(5-(4-(trifluoromethyl)phenyl)-2-naphthamido)ethyl)pyridin-2-yl)amino)piperidine-1-carboxylate

References

1. Wenzhi Ji, et al. Angew Chem Int Ed Engl. 2023 Sep 1;e202308292.

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