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Chemical Structure : PDE10A-IN-31
Catalog No.: PC-62737Not For Human Use, Lab Use Only.
PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A.
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PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A.
PDE10A-IN-31 dispalys >2,000-fold selective over PDE1B/2A/3B/4D/5A/7A9A, weak activity on CYP isoforms.
PDE10A-IN-31 displays excellent pharmacokinetic properties.
| M.Wt | 477.524 | |
| Formula | C28H23N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Meegalla SK, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4216-22.
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