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PDE10A-IN-32

Chemical Structure : PDE10A-IN-32

CAS No.: 1338795-39-3

PDE10A-IN-32 (PDE10A inhibitor 32)

Catalog No.: PC-63306Not For Human Use, Lab Use Only.

PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).

    Physicochemical Properties

    M.Wt 470.977
    Formula C24H28ClFN6O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine hydrochloride

    References

    1. Kadoh Y, et al. Chem Pharm Bull (Tokyo). 2018;66(3):243-250.

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