PDE10A-IN-32 |CAS:1338795-39-3 Probechem Biochemicals

Chemical Structure : PDE10A-IN-32

PDE10A-IN-32 (PDE10A inhibitor 32)

Catalog No.: PC-63306Not For Human Use, Lab Use Only.

PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).

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Biological Activity

PDE10A-IN-32 is a potent, highly selective, brain penetrant PDE10A inhibitor with IC50 of 0.14 nM, displays no significant activity against other PDEs (IC50>1,000 nM).

Physicochemical Properties

M.Wt	470.977
Formula	C24H28ClFN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine hydrochloride

References

1. Kadoh Y, et al. Chem Pharm Bull (Tokyo). 2018;66(3):243-250.

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PDE10A-IN-32 (PDE10A inhibitor 32)

Biological Activity

Physicochemical Properties

References

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